Litter is the main carbon source for soil respiration. Soil respiration rate is affected by increasing atmospheric nitrogen deposition which through changing the input and decomposition of forest litters. To reveal the effects of nitrogen deposition and litters management on soil respiration rate, a 15-years old Cryptomeria fortunei plantation was selected as the research object in state-owned Zhazuo forestry farm of Guizhou Province. Four nitrogen addition treatments were set up in the Cryptomeria fortunei plantation, which were Control plots (CK,0 gN m^-2 a^-1), low nitrogen plot (LN, 15 gN m^-2 a^-1), medium nitrogen (MN, 30 gN m^-2 a^-1) and high nitrogen (HN, 60 gN m^-2 a^-1), respectively. Meanwhile, litter removal and litter control group (no litter treatment) were designed in each nitrogen addition treatment. Soil respiration rate were measured by Li-8100 from March 2021 to February 2022. The effects of nitrogen deposition and litter treatments on soil respiration rate were analyzed based on the measured data, and the main influence factor was determined according to the analysis. The results showed that the temporal variations of soil respiration rate were not influenced by nitrogen addition and litter removal, the maximal monthly values of soil respiration rates all appeared in July and the minimal monthly values all appeared in February among different nitrogen addition treatments. Nitrogen addition had no significant influences on soil respiration rate (P > 0.05), whereas litter removal decreased soil respiration rate significantly (P < 0.05) except CK plot. The contributions of litter to total soil respiration rate were 8.6%-28.5% in different nitrogen addition treatments, and the largest contribution of litter appeared in LN plot. There were significant exponential relationship between soil temperature and soil respiration rate at 5cm soil depth in all nitrogen addition levels, and 58.5%-79.5% variations of soil respiration rate were explained by soil temperature model. The soil respiration rate showed significant negative linear relationships with soil moisture at 5cm soil depth in all nitrogen addition levels, and changes of soil respiration rate could be interpreted 26.4%-39.5% by soil moisture. The determination coefficient of the bivariate model based on soil temperature and soil moisture was larger than single factor model, and 59.1%-85.8% variations of soil respiration rate were explained by the bivariate model in all nitrogen addition plots. It is conclude that temperature is the main factor affecting soil respiration rate, and litter management is the key process to regulate soil respiration under the background of increasing atmosphere nitrogen deposition.