Nansi Lake was selected as our study site for this study. Droughts, floods and water pollution for this site were used as a source of the ecological risk (ER) with information by the technologies of remote sensing images and geographic information system. Landscape indices were developed to evaluate ecosystem status and fragile ER receptors. Based on the principles of the measurement of ER, the ER values for Nansi Lake were obtained by integrated comprehensive loss probability and the ER degree. The results showed that the ER for Nansi Lake area had significant differences between upper and lower lakes with spatial distributions. It also showed that ER for Nansi Lake had a spatial and regional heterogeneity.