A total of 106 individual farmers' fields were surveyed in Zhanyi and Xundian counties (the main japonica-rice-producing areas of the Yunnan plateau) of Yunnan province. The data pertaining to pest injuries and yields was collected and analyzed using two analytical approaches. The first approach was intended to characterize relationships between injury profiles and yield levels using cluster and correspondence analyses, while the second approach was aimed at generating yield loss estimates using combinations of principal components and step-wise multiple regressions. Seven pest injury profiles (abbreviated as IN) were determined using cluster analysis; IN1, IN2, and IN3 were lower injury levels of pest combinations in seven profiles, while IN5, IN6, and IN7 were higher injury levels. Clusters of injury profiles (IN1-IN7) and yield levels (Y1-Y5) are plotted on the two first axes of correspondence analysis between patterns of injury profiles (IN) and yield levels (Y). The correspondence analysis yielded a path of increasing yield levels (Y1 to Y5) associated with varying combinations of injuries in the plane defined by axes 1 and 2. This would suggest that injury profiles (IN5, IN6 and IN7) located on the left in the factorial plane may cause more considerable damage than others (IN1, IN2 and IN3) located on the right. The principal component analysis with multiple regressions generated estimates of yield reductions due to rice diseases, insects and weeds. The results showed that injuries caused by weeds above rice canopy, stem borers (white heads), leaf folder, bacterial leaf blight, army worms, leaf blast and plant hoppers were the most damaging factors in this region. Results of this study will provide some foundations for developing pest management strategies and improving rice production level at the regional scale.