Abstract:The impact of starvation and refeeding on larval growth, survival, and metamorphosis of clam Cyclina Sinensis was investigated at 18.2-20.6℃, salinity 23-25, and pH 7.96-8.14. The larvae were not fed for up to 13 days at 1-day intervals, followed by refeeding for the remaining of a 28-day period. The results showed that unfed clam larvae grew for about 7 days to 139.5 μm by using endogenous nutrients and then the shell length plateaued. The larvae that were not fed for 13 days were able to develop from the umbo-vellger to plantigrade larvae. However, as the starvation period prolonged, larval survival rate and the size of plantigrades, metamorphosed larvae, and single-siphon juveniles decreased. The calculated point-of-no-return (the threshold during starvation after which larvae can no longer metamorphose even if food is provided) for the larvae was 12.48 days, and the duration of delayed metamorphosis reached 12.7 days. During the refeeding phase following various starvation periods, the larvae were able to recover growth and metamorphosis, exhibiting the compensatory growth. Juveniles that were not fed for 1, 2, 3, 10, 11, or 12 days during the larval stage were able to catch up the size of juveniles that were fed daily during the 28-day period. However, juveniles that were not fed for 4-9 days during the larval stage surpassed the size of juveniles that were fed daily. During the 4-9 days of starvation, growth rate of juveniles increased with increasing days of starvation. These results indicate that Cyclina Sinensis larvae and juveniles have the capacity to completely compensate for loss of growth and metamorphosis for up to 12 days (post-hatch) of starvation. However, starvation during this early life stage dramatically diminishes survival.