Warming has already caused changes in global precipitation patterns. Soil respiration, as the largest carbon reservoir of CO₂ released by terrestrial ecosystems to the atmosphere, will further affect the carbon cycle in response to precipitation changes, thus producing feedback to global climate change. Although there were a lot of studies on the relationship between soil respiration and precipitation change in the past, there are a lot of controversies. Therefore, it is urgent to further explore the response of soil respiration to precipitation change. Here, the meta-analysis method was used to integrate 284 published papers and 367 sets of data from the English database of Web of Science and the China National Knowledge Network Literature Database (CNKI) to analyze the response of soil respiration to precipitation change in middle and low latitudes around the world. The results showed that the response of soil respiration to precipitation change presented asymmetric characteristics,the increase of precipitation increased the soil respiration by 16.7%, while the decrease of precipitation inhibited the soil respiration by 17.88%. The study also found that the responses of soil respiration to precipitation change in different ecosystems and climate zones were quite different. Among them, the increase of precipitation could improve the soil respiration of grassland ecosystem by 22%, which was 12% higher than that of forest ecosystem. While the decrease of precipitation will weaken the soil respiration of grassland ecosystem by 28%, which was 16% higher than that of forest ecosystem. Compared with humid areas, the increased of precipitation had a greater effect on soil respiration in arid areas. But the decrease of precipitation had no significant difference on soil respiration in arid and humid areas. In addition, this study also indicated that there were differences in the response of soil respiration to different precipitation intensities and years. In different precipitation intensities,regardless of increased precipitation or decreased precipitation, the soil respiration of heavy increased precipitation and decreased precipitation changed the most. that is, heavy increased precipitation and decreased precipitation (＞75%), moderate increased precipitation and decreased precipitation (25%-75%), and slight rainfall decreased and increased (＜25%); In different precipitation years, the long-term increased precipitation had the most prominent effect on soil respiration, while long-term decreased precipitation had no significant difference on soil respiration. The results can provide importantly scientific basis and theoretical basis for accurate prediction of soil respiration change of terrestrial ecosystem and improvement of model simulation under future climate scenarios.