The living space of human and wildlife highly overlap, which caused the inevitable conflict between human and wildlife. How to move from conflict to coexistence is a hot and difficult issue in academic research. This paper reviewed the research progress from the concept analysis, quantitative evaluation, impact factors, and realization mechanism of human and wildlife coexistence. The research results showed that the concept definition and quantitative evaluation of human and wildlife coexistence were still controversial. Most studies believe that coexistence does not mean the absence of conflicts, but rather the inevitable conflicts are controlled within a tolerable range. Most of the studies use variables such as tolerance, acceptance, conservation attitude, and behavior to quantify the human and wildlife coexistence. In terms of the influencing factors of coexistence, the costs and benefits related to wildlife are the key factors affecting the human and wildlife coexistence. Economic and educational means are important paths to achieve coexistence. Economic means, including compensation, insurance, ecotourism, and conservation investment, can achieve coexistence by increasing the benefits and reducing costs of wildlife conservation. In addition, nature education can achieve coexistence by improving the community conservation awareness, enhancing the ability to cope with conflicts, and sensing the benefits of wildlife conservation. Future research can be carried out in the following aspects: (1) build an indicator system combining subjective and objective indicators from the perspective of ecology and livelihood to quantify the human and wildlife coexistence. (2) Identify the key factors affecting the human and wildlife coexistence and summarize successful coexistence experience based on the social-ecological system framework. (3) Adopt the experimental economics method to explore the local specific diverse portfolio of coexistence interventions.