Airborne pollen in cities has become one of the main allergens of seasonal allergy in spring and autumn. Studying pollen dispersion characteristics under typical building layouts and their plant configuration patterns can provide data support for rational optimization of urban green space configuration and complement pollen dispersion studies. Based on the spring observation data of the campus green space in Haidian District, Beijing, the street valley layout and plant characteristics parameters of three sampling sites were extracted, and 15 parametric scenarios of typical shallow street valley layouts and their plant configuration patterns were constructed with the help of Computational Fluid Dynamics platform to explore the pollen dispersion characteristics and distance thresholds under different scenarios. The results show that:① the area with high pollen concentration is located in the area with low wind speed and poor air mobility, and the area with low pollen concentration is located in the area with high wind speed and good air mobility. ② The pollen dispersion characteristics of four plant configuration patterns are shown as street tree type > scattered > street tree+group planting > grouped type, and the pollen deposition characteristics are shown as grouped type > street tree+group planting > street tree type > scattered. The highest pollen concentration reduction rate of 24.89% was achieved by staggered layout combined with street tree type planting configuration, and the dispersal effect was relatively better. The back-shaped layout combined with group planting configuration has the lowest pollen concentration reduction rate of 7.31%, and the aggregation effect is relatively better. ③ Influenced by different buildings, plants and wind field, the pollen dispersion distance of three types of building layout is in the order of rowed > back-shaped > staggered, rowed need about 35-75m dispersion distance, back-shaped need about 28-60m dispersion distance, staggered need about 20-53m dispersion distance. Plants with low wind speed, high pollen concentration and close dispersion distance are easy to accumulate, while plants with high wind speed, low pollen concentration and long dispersion distance are easy to disperse.