Large-scale mangrove ecological restoration projects have been carried out in the intertidal zones of Kaozhou Bay since 2017. However, the environmental responses of macrofaunal communities in the Kaozhou Bay mangrove wetlands have not been reported. Based on quantitative sampling data of macrofauna from two mangrove wetlands planted with mangrove trees for 1-2 years (transect X) and 5-6 years (transect Y) near Yanzhou Bridge during four seasons of 2018-2019, we analyzed the spatial and temporal patterns of macrofauna and their environmental effects in artificial mangrove wetland. Two-way ANOVA analysis showed that the species number, density, biomass, diversity index (H') and richness index (d) of macrofaunal communities in winter and the density in summer at transect Y increased with the decrease of tidal height, while the evenness index (J) in winter, H' and J in summer at transect Y decreased with the decrease of tidal height. Cluster and non-metric multidimensional scale (nMDS) analyses showed that the similarity of macrofaunal communities between transect X and transect Y was low in winter and summer, but high in spring and autumn. The maximum spring tide, tidal range, the species number, density, H' and d of macrofauna in winter and summer were higher than those in spring and autumn. The species number, H' and J of macrofauna in wetlands planted with mangrove trees for 1-2 years (transect X) were lower than those planted with mangrove trees for 5-6 years (transect Y). These results confirm that the tides and mangrove planting years affect the community structure of benthic macrofauna in mangrove wetlands in Kaozhou Bay. These results can provide basic data for the conservation and ecological restoration of macrofauna.