The intensive anthropogenic activities have triggered dramatic variations of land-use types in mine-agriculture-urban compound areas, which further exerted adverse effects on ecosystem service values and threatened the stability and sustainable development of regional ecosystem seriously. It is significant for balance between regionally ecological functions and human demands to analyze and predict the temporal and spatial evolution characteristics, trade-offs and synergies of Ecosystem Service Value (ESV) in mine-agriculture-urban compound areas. Therefore, we analyzed and predicted the variations of land-use types and ESV in the mine-agriculture-urban compound area in north Shanxi from 1990 to 2026 based on the Future Land Use Simulation (FLUS) model and the valuation scale estimation. In addition, we explored the tradeoffs and synergies between ecosystem services of multiple scenarios in 2026 using correlation indexes. The results demonstrated that (1) the land use pattern changed significantly from 2018 to 2026, which was mainly characterized by the frequent conversion among agriculture land, damaged land and other land-use types. In 2026, the ESVs of the study area showed dramatic variations under different development scenarios. The total ESVs of nature, economy and ecology development scenario in 2026 were 187 million yuan, 169 million yuan and 201 million yuan, respectively. (2) Land reclamation created about 195 million yuan from 1990 to 2018, of which 186 million yuan was achieved in the first stage while 9 million yuan was achieved in the second stage. In spite of the lower ESV increase amount compared with the first stage, the increased ESV in the second stage accounted for an increasingly larger proportion, indicating that the second stage had remarkable potential in improving the total ESV. Besides, the conversion processes from grassland and cultivated land into forest land were the main driving forces for the ESV increase in the second stage and the increased ESVs were 4.30 million yuan and 4.05 million yuan in the two processes.(3) Each kind of ecosystem service showed the synergistic relationship obviously. The southwestern region with less human disturbance and the mining area with severe human disturbance showed the synergistic relationship. Only a few regions showed trade-off relationship, where the most obvious trade-off relationship was found between regulation and culture. This paper provided a certain support to the management of ecosystem service in mine-agriculture-urban compound area.