Based on the land use data from 2010, 2015 and 2020, this study takes Zhengzhou as the research area and analyzes the spatiotemporal changes patterns of Production-Living-Ecological and eco-environmental quality from 2010 to 2020, using land use transfer matrix and eco-environmental effect methods. In addition, based on the data of land use in 2015, the Future Land Use Simulation (FLUS) model was adopted to simulate the pattern development of Production-Living-Ecological space in 2035 by combining three scenarios of natural development, production space priority, and ecological protection. The regionally eco-environmental quality index and ecological contribution rate were calculated under the three scenarios. The results showed that:① from 2010 to 2020, the production space area in Zhengzhou showed a decreasing trend, while the living space kept going up, and the ecological space firstly increased and then decreased. ②The eco-environmental quality index continuously declined from 0.3097 to 0.3065 from 2010 to 2020. The low-quality areas gradually increased. The reduction of agricultural production land, other ecological land and water ecological land were the main factors leading to the deterioration of eco-environment quality in Zhengzhou. Under the natural development scenario, the living space shows the expanding trend, while the production and ecological space gradually declined. In the production priority scenario and ecological protection scenario, the living space reduced, while the production and ecological space continuously increased. Among the three scenarios, the eco-environmental quality index of Zhengzhou in 2035 under the ecological protection scenario will be the highest, and its eco-environmental quality level under this scenario will be also constantly improving. Simulating future land use pattern change and its eco-environmental effects will be helpful for optimizing the existing land use spatial pattern and promoting the sustainable urban development.