Aerosols and ozone are two major atmospheric pollutants in most regions of China, which have serious impacts on the city ecological environment and human health. Taking Shenzhen as the study area, the spatial and temporal distribution of PM_2.5 and ozone in the last five years (2015-2019) were studied at annual, seasonal, and monthly scales using monitoring data provided by observation stations and the ordinary Kriging spatial interpolation method. In addition, the landcover and its landscape were analyzed at monthly scales by Pearson analysis and significance test. The results show that: (1) in the past five years, PM_2.5 concentration in Shenzhen show a general decreasing trend, while ozone concentration increase after an early decrease, they both have significant seasonal and monthly differences. (2) The spatial differences between PM_2.5 concentration and ozone concentration on the annual, seasonal and monthly scales are obvious, and the PM_2.5 concentration is overall high in the northwest and low in the southeast of Shenzhen, while ozone concentration is higher in the northwest and southeast but relatively low in the rest of Shenzhen. (3) The increase of vegetation occupancy has a significant inhibitory and regulatory effect on PM_2.5 concentration, and the closer the distance between vegetation patches, the regulatory effect on PM_2.5 concentration becomes more obvious; the increase in the proportion of water bodies may lead to higher and more variable ozone concentration. This study can provide reference for urban air pollution control and landscape pattern planning and management.