The development of urbanization leads to the continuous expansion of city scale. Than formal city clusters which have become a major form of urban development in China with heavy fine particle PM_2.5 pollution. Beijing-Tianjin-Hebei region is one of the most polluted city clusters in China. PM_2.5 is identified as the major air pollutant in recent year. It not only affects the development of natural economy and society, but also affects the human respiratory system, cardiovascular system and central nervous system. The research of air pollution on regional scale is more complicated. However, the comprehensive impact between urban development and PM_2.5 changes have not been well examined. It is difficult to assess the negative effects of air pollution, regional air pollution sources and impact mechanisms. Therefore, this research uses spatial analysis by constructing an evaluation model. We study residents' exposure risk, contribution of human activities to PM_2.5 and source and sink features of five land-use types in 168 counties in 2000, 2005, 2010, and 2015. Meanwhile, we analyzed their variation and the corresponding weights were given for comprehensive evaluation. The results showed that: 1) both the risk and air pollution distribution increased rapidly from 2000 to 2014, especially in North and South Beijing-Tianjin-Hebei region. The comprehensive impact continued to rise, especially in Central and South Beijing-Tianjin-Hebei region. 2) The region and role of "source and sink" are constantly changing. Therefore, different land types have different source and sink characteristics, which have different contributions to environmental issues. Air quality research should be carried out simultaneously with the development of urbanization, and coordinated with the development of urbanization. This research has established a related evaluation system. We want to carry out quantitative research between urban development and air pollution to provide scientific support for the sustainable development of cities. We hope the results in this work could serve as an example to the internal changes of air pollution and ecological pattern.