Many studies focus on effects of temperature and moisture on litter mass loss rate, however, how they affect CO₂ emission rate and leaching of dissolved organic carbon (DOC) during the litter decomposition is unclear. We conducted an incubation experiment with four temperature gradients (0, 5, 10 and 20℃) and two moistures (25% and 40%) using litter of alpine meadow for 96 incubation days. Our results showed that litter mass loss rate only increased with increases in temperature under high moisture. The temperature sensitivity of CO₂ emission rate was 2.3 times under high moisture as that of low moisture. The effect of moisture on temperature sensitivity of DOC leaching was small. The temperature sensitivities of CO₂ emission rate were about 10 and 20 times compared with that of DOC leaching under 25% and 40% moistures, respectively, suggesting that more CO₂ could be emitted relative to DOC leaching under future climate change. Therefore, more studies are needed to explore how climate change affects CO₂ emission and DOC leaching through litter decomposition and their underlying mechanisms in the future.