To protect the fishery resources and ecological environment around the Zhoushan Archipelago, we conducted a comprehensive ecological survey in the Zhoushan sea area from 2014 to 2017. We examined both the temporal and spatial changes in the zooplankton community at 33 sampling stations. During each of the four cruises-in the spring, summer, winter, and fall-we identified 88 species of zooplankton adults and 19 species of zooplankton juveniles, including 12 dominant species. The dominant species and zooplankton community characteristics changed significantly with the seasons. The replacement rates of dominant species were 75% from spring to winter, 80% from summer to autumn, 100% from autumn to winter, and 60% from winter to spring. The average biomass from highest to lowest was 176.34 mg/m³ in summer, 120.20 mg/m³ in spring, 86.28 mg/m³ in autumn, and 7.21 mg/m³ in winter. The average abundance from highest to lowest was 143.97 ind/m³ in summer, 86.30 ind/m³ in spring, 21.38 ind/m³ in autumn, and 26.86 ind/m³ in winter. The average diversity index was the highest in summer (3.03), followed by autumn (2.82), spring (2.05), and then winter (1.71). The zooplankton community in the Zhoushan sea area exhibited significant seasonal and regional differences. Temperature, salinity, Chl a, and nutrients were the main environmental factors influencing the spatio-temporal variation in the zooplankton community around the Zhoushan Archipelago. The spatial distribution of the zooplankton community was mainly affected by salinity in spring; temperature, salinity, and Chl a in summer; Chl a in autumn; and suspended solids and dissolved oxygen in winter. Meanwhile, the nutrients had a certain influence in each season.