In Northeast Asia (Northeast China and the northeast of Inner Mongolia, Japan, the Korean Peninsula, Mongolia, and the Russian Far East), there are a wealth of species in the family Soricidae. In Northeast Asia, studies on the molecular ecology of the Soricidae have increased rapidly along with on going advances in molecular biology methods. In this study, we review the molecular phylogeny, genetic diversity, and molecular phylogeography of the Soricidae. Four expectations regarding future developments in the molecular ecology of Soricidae are proposed in this paper:(1) the study of Quaternary glacial refugia in Northeast Asia; (2) study of the comparative phylogeography of Soricidae distributed in the same region; (3) the phylogeographical status of Soricidae in Northeast Asia and Northeast China; and (4) the development of new molecular markers and new analytical methods.