Since the end of the 20th century, giant jellyfish blooms have occurred on a nearly annual basis around the globe and have had disastrous effects on the ecology of marine systems, fishery resources, coastal industries, and coastal tourism. Researchers, both domestically and abroad, have thoroughly investigated this phenomenon using nets, visual observations, underwater cameras, acoustic technology, and aerial imagery, among other techniques to elucidate the underlying mechanisms of these blooms. In recent years, acoustic technology has been used to investigate cultured giant jellyfish stock and their behavior in fisheries in Europe, the United States, Japan, and Korea. These technologies have demonstrated favorable monitoring capabilities and the potential for their application in both resource assessment and the kinematics of the species. Until very recently, studies using acoustic monitoring to investigate giant jellyfish were still lacking in China. In this study, we introduce research regarding the acoustic assessment, spatial distribution, and behavioral acoustic telemetry of giant jellyfish to provide a theoretical and scientific basis for the use of acoustic technology for their monitoring and assessment in China. The acoustic target strength of jellyfish is much lower than that of fish because of the lower reflectivity of the jellyfish as a result of its high water content (> 95%). However, it is clear now that many species of giant jellyfish are able to produce significant sound scattering at frequencies routinely employed for fisheries assessments. Several studies have shown that the acoustic target strength of giant jellyfish has a positive relationship with its bell diameter. Acoustic monitoring and assessment of giant jellyfish have been more effectively conducted in regions with a dominance of the cnidarian, and in most cases, a combination of nets or video images and other methods were used. Because of the favorable application of a scientific echosounder, high resolution imaging sonar, and ultrasonic pinger in the acoustic monitoring and assessment of giant jellyfish internationally, we recommend their use in China as well. Several suggestions are proposed to support the use and further development of acoustic technology for the study and assessment of the giant jellyfish, including studies of ecological behavior, monitoring, and forecasting and warning systems in key coastal areas to improve the current monitoring systems for giant jellyfish in China.