The bottleneck of the "Thirteenth-five" Program of Rock Desertification Control is to unveil the watershed scale water-soil-biology pattern and develop water-soil-biology restoration technologies corresponding to local conditions. The National key research and development program of China (2016YFC0502300) integrates multi-disciplinary teams to explore the land rocky desertification landscape restoration and for pilot test in the karst trough valley, two key scientific questions and five technologies are the foci of this program. The project will probe the relationships between the distributions of water-soil-biology and landscape and geology, and elucidate the mechanism of the ecological deterioration during the land rocky desertification process, and develop high efficient techniques on soil and water resources utilization and the soil flow/loss prevention upon/underground. Appropriated technologies for better combination the advantages of aboriginal wild rootstocks and economic tree species will be developed, with special aim to reconcile the seemingly conflicting interests between economy development and ecological protection, a sustainable ecosystem and eco-industry model in karst trough valley will be established, which will provide a scientific and technological support for regional ecosystem restoration and poverty elimination.