Global climate change is an indisputable fact and this change has a significant impact on terrestrial ecosystems, especially the material cycles of forest ecosystems. Because soil enzymes play a predominant role in soil material cycles, the responses of forest soil enzymes to environmental change have been receiving increasing attention recently. These responses are key for the prediction of the impacts of future climate change on forest ecosystem processes. Therefore, this review summarizes the latest research on the responses of forest soil enzymes to environmental change, especially global warming and nitrogen deposition, and provides some suggestions for future areas of research. Environmental change will lead to changes in soil pH, moisture, and nutrients, but these changes will feed back into the activity and stability of soil enzymes. The responses of forest soil enzymes to warming are comprehensive, not only related to the type of enzyme and the range and duration of the increased temperature but also to soil types. The responses of soil enzymes to nitrogen addition are related to the types of forest and soil, and the effects of compound nitrogen deposition are greater. Future research should strengthen the dynamic response of enzymatic characterization and pay more attention to the different enzymatic responses induced by different forests and soils and to interactions between multiple factors. Additionally, long-term comprehensive observations are necessary.