Regional land ecosystem is facing deterioration from the rapid growth of urbanization. In order to promote sustainable development of the land ecosystem, it is necessary that we evaluate regional land ecological security. Many researchers have studied and evaluated for regional land ecological security; however, most of the evaluation was based on watershed and county scale, and few researches focused on the township scale. In this study, Bortala Mongolian Autonomous Prefecture (i.e. Bortala) in Xinjiang Uygur Automous region was taken as study area, and Remote Sensing (RS), Geographical Information System (GIS), and Global Position System (GPS) technologies were adopted to analyze temporal and spatial perspectives of land ecological security in Bortala. On the basis of the natural geographic features and socio-economic situation of Bortala, we constructed the pressure-state-response (P-S-R) land ecological security evaluation model (township scale) in Bortala. Based on the two period's data of statistic yearbook and remote sensing in 2011 and 2014, we first constructed the index system, using 25 indices reflecting regional P-S-R. The entropy weight and analytic hierarchy process methods were used to determine the indices weight of Bortala P-S-R model. Finally, the land ecological security index of Bortala was calculated with the data obtained from the P-S-R model by GIS Grid. The results show that: (1) The land ecological security index had deteriorated from 2011 to 2014 in Bortala. Between 2011 and 2014, 2555.33 km² of level III (grade of security) transferred to level IV, which deteriorated areas mainly concentrated in Wenquan County; 1356.53 km² of level V transferred to level IV, which improved areas concentrated in the Mangding town and Tuotuo town of Jinghe County. (2) The land ecological security index of most towns was at level III in Bortala, which respected the ecological structure of these towns were not stable. (3) The spatial difference of land ecological security index was obvious in Bortala, the worst places were located in the eastern desert, and the best places were concentrated in the central oasis and lake. The evaluation results and major environment problems may help the local government finding inappropriate and inadequate for Bortala development. Bortala Prefecture is a drought-prone and ecologically vulnerable region in the Northwest region. Temporary land use regulation cannot guarantee long-term regional ecological balance and security. In this study, we recommend increased attention on regional ecological protection and sustainable development for villages and towns.