In order to investigate the global ecological suitability and characteristics of regions for the medicinal plant Angelica sinensis,a maximum entropy model (MaxEnt) and geographic information system (GIS) technology were used to investigate global ecology suitability regions based on 109 sample points of A.sinensis and 37 ecological factors.The results showed that global ecological regions that are suitable for A.sinensis are located mainly in the range of 20-50°N and 15-35°S,which includes sections of North America,Europe,Asia,South America and Africa.The total area of suitable regions found was about 5930700 km².The regions with the most similarity were found to be mainly in the south of Gansu province,Sichuan,the east of the Tibet Autonomous Region,the north of Yunnan province,Guizhou,the southwest of Shanxi province,and other nearby regions.These results signify that China is very suitable for the cultivation and production of A.sinensis.The climatic factors that were found to affect the distribution of A.sinensis were mainly precipitation during warmest quarter,mean temperature of the coldest quarter,and the coefficient of variation of precipitation seasonality,with the most suitable value ranges being 300-700 mm,-3-7℃ and 70-98 respectively.The soil factors affecting the distribution of A.sinensis were found to be mainly the calcium carbonate (lime) content and percentage clay,the value ranges of which were found to be 60%-0% and 17%-24%,respectively,in the ecologically suitable regions.These results provide a scientific reference for the refinement of the artificial cultivation of A.sinensis.