In China today, environmental pollution have become important factor that restrict sustainable development in China. Accurate analysis of the impact of human factors on the regional environmental pollution in province is an important part of the current research on sustainable development. The GWR measurement model is more accurate than the traditional ordinary least squares (OLS) model because of its spatial factors. According to the theory of loss of environment pollution in currency, we estimated loss of environment pollution of 31 provincial regions in China in 2013 and explored the features of spatial distribution of the Chinese environmental pollution using the method of spatial autocorrelation analysis. We quantitatively examined the impacts of China's population, affluence, and technology on the environment pollution by constructing a STIRPAT model based on the GWR. The main conclusions are as follows: (1) the economic loss caused by environmental pollution in China in 2013 is ￥2812.48×10⁸yuan. The noise pollution is the main factor causing the loss of environmental pollution. (2)there are spatial correlation and spatial heterogeneity, and the spatial distribution of regional environmental pollution in the provinces is the pattern of the East High and West Low. (3)human factors to the provincial environmental pollution has significant effect, population and economic growth and promote urbanization will exacerbate the provincial environmental pollution, and industrial structure upgrading and expanding the opening to the outside world will help to alleviate some of the provincial environmental pollution. (4) the influence of human factors on the provincial environmental pollution has a spatial heterogeneity. Population of the extent of the impact of the provincial environmental pollution from the northwest to the southeast gradually increases; affluence on the influence of the provincial environmental pollution from west to east echelon increase; industrial structure on the impact of the provincial environmental pollution from east to west is gradually increasing; urbanization of the provincial environmental pollution influence from west to east gradually reduced; opening to the outside world on the influence of the provincial environmental pollution from east to west increases gradually. (5) the calculation results based on the existing samples are conditional to support the EKC hypothesis.