City is a kind of social-economic-natural complex ecosystem (SENCE), supported by 5 kinds of eco-factors (water, soil, fire, biome and minerals), 5 eco-processes (production, transportation, consumption, recycling and regulation), 5 kinds of function (economy, politics, culture, society and environment), and coupled in time, space, quantity, structure and function). This paper explained its integrative dynamics, cybernetics and systematics, three supporters of its development: eco-security (cleaning, greening, vitalizing, beautification and forward evolution), circular economy (coupling five chains of biological, mineral, service, recycling and wisdom), and harmonious society (with a integrative management model of pollution control, cleaner production, eco-industry, eco-polis and eco-civilization). Urban ecological management is rather a kind of regulation, restoration and creation process to enforce the urban ecological service of cultivation, regulation, circulation, supply and supporting than just nature conservation. Urban eco-space includes the physical space the city occupied, the hinterland ecosystem for city metabolism using, and the super eco niche for the city function. Through case studies of Tianjin, Yangzhou, Huaibei and Hefei, the paper has shown the approaches for urban eco-space planning and management. Finally, the application of integrative eco-niche and eco-potentials are discussed with a case of Yanqing County for its development relationship with its mother city of Beijing.