Landscape heterogeneity consists of landscape composition and configuration, while human disturbance is one of the main factors affecting landscape heterogeneity. So far there are few of studies on landscape heterogeneity under the different disturbances by using moving window. Selecting Gongyi City of Henan Province as the study area, this paper is aimed to reveal the characteristics of the agro-landscape heterogeneity under the different intensity of human disturbance. We set up a 4km×4km sample area in urban area, farmland, hilly and mountains respectively. By using moving window, we count the contagion index and the evenness index at landscape level. The moving window radius divided into 100m, 250m, 500m, 1000m, 1250m and 1500m. In order to reflect the features of landscape composition and landscape configuration on multiple scales, we calculate the contagion index and the evenness index in the moving windows radius. Meanwhile the correlation of the two indexes is also studied by curve estimate. The β of the fitted curve illustrates that the contagion index changes along with the evenness index on the contrary, that is to say, landscape composition changes consistent with landscape configuration in the opposite direction. The study results are as follows: 1) Along with increasing of the moving radius, the maximum of contagion index and evenness index decline gradually in the four landscapes, while the minimum of the two indexes show the opposite trend but urban area; 2) The mean values of contagion index in the urban and farmland landscapes are bigger than the values of the hilly and mountainous landscapes. Otherwise, the mean value of evenness index is showing opposite characteristics from the contagion index; 3) The relationship of the contagion index and the evenness index is significantly negative (R² > 0.9) in the four different landscapes. However above the radius of 100m in urban landscape, the correlation of these two indexes in non-significantly negative (R² < 0.9). 4) The β values of the curve estimate show increasing trend from the radius of 100m to 1500m in the four different landscapes. When the moving window radius increases gradually,there are large numbers of various patches in the landscapes bringing about the whole change of landscape composition and configuration, and this would have an effect on the biodiversity, ecosystem stability and ecological system service. At the landscape level, the more complex landscape composition and configuration, the higher level of landscape heterogeneity. That means the numbers and the types of patches are various, and these patches are grouped in different types. The heterogeneity of hilly and mountains are higher than urban area and farmland, it proves that the human disturbance factors play an important role on the formation of landscape heterogeneity. Because of the human activities make the single type of land use, which reduces the landscape heterogeneity. As above said landscape heterogeneity has a very strong dependence on scales, so analyzing the landscape heterogeneity on multi-scale is very meaningful. We wish our study results can provide theoretical basis for a sustainable landscape management of agro-landscape in future.