Wetland is one of the three most valuable ecosystems in the world. Blessed with numerous lakes, Wuhan has enjoyed the reputation of "City with hundreds of lakes", and "Lake" is the important name card of Wuhan. Based on the Landsat TM images of the year of 2000, 2005, and 2010, we get the lakes variation characteristics from year 2000 to year 2010 of central Wuhan with the method of NDWI to extract prominent information of lakes and then create the vector layers of the lakes data of the three years, which are used to calculate the Shrinking Rate of the lakes, fractal dimension of lake patches and the degree of fragmentation of lake landscape. The study shows that: (1) All the lakes have shrunk, and there are different shrinking rates of different lakes, which are mainly decided by which loop are these lakes in and policy factors. (2) fractal dimensions of these lake patches are range from 1 to 1.3, and are increasingly close to 1. It shows that the lakes are becoming regularly shaped under human activity influence. (3) There is an increase in the number of lake patches. With their decrease in area, the lakes become fragmented at the same time due to the traffic construction. When a lake is fragmented, it is easier to be polluted for the reduction of its self-purification capacity and probably to be filled in at last. In one word, the landscape environment of lakes proceeds in a negative direction. Stricter policies should be put forward for administration and protection of the lakes of Wuhan City.