Plateau wetland provides an ecological protection barrier for the safety of watershed. As appearance of global climate warming and climatic anomaly, to understand the physiological and biochemical response of aquatic plants in the plateau region to the climate change and the harms under the temperature stress is critical for maintaining the plateau ecosystem and dealing with the climate change. 4 dominant plant species of Scirpus tabernaemontani, Zizania caduciflora and Heleocharis liouana, Sparganium simplex with their original soils in the lakeside of Napahai, a typical wetland in plateau region of northwestern Yunnan were selected to study the impacts of regional climate condition variations on physiological and biochemical properties of those plants. Got with local climate conditions of Napahai in Shangrila those plants with their growing soils were removed as a soil-plant unit to Lashi Lake in Lijiang and Dianchi watershed in Kunming where the climate conditions are different. Comparing with original growing area, the variations of index of physiological and biochemical to indicate adversity stress, including MDA, Pro, SS and POD were analyzed under the impacts of climatic change. The results showed that even though wetland plant is azonal plant but affected significantly by the climate change and the response to the climate change was different from plants. Such widespread species as Scirpus tabernaemontani and Zizania caduciflora could well adapt to climate warming and grow better. With temperature rise, both of their biomass increased to 196% and 190% in Lashihai Lake and 487% and 408% in Dianchi watershed, respectively. But content of MDA, Pro,POD all fell from 16%, 27%, 14% in Lashi Lake to 31%, 52%, 48% in Dianchi watershed for Scirpus tabernaemontani, and 24%, 12%, 58% in Lashihai Lake to 24%, 25%, 73% in Dianchi watershed for Zizania caduciflora, respectively. In spite of the stress of climate change, Heleocharis liouana, another widespread species could resist the alterability through its own metabolic regulations, which reflected the strong climate adaptability of widespread species. By contrast, Sparganium simplex, a narrowly spread species sustained great damage for it was too sensitive to the climate change. With the temperature rise the biomass rising at beginning to 17% in Lashihai Lake, and then dropped to 20% in Dianchi watershed. MDA and Pro decreased at beginning to 0.001387 μmol/g and 13.386891 μg/g, and then increased to 0.002739 μmol/g and 18.172878 μg/g, respectively. For such a narrow distribution species, it would face the survival crisis along with the change of the climate conditions. That reflected the fragility of plateau wetland ecosystem and its importance under global warming. Thus, the potential ecological risk behind the maintaining of plateau wetland ecosystem was revealed.