The Symposium on Modern Ecology Series was initiated by Li Bo, a well-known Chinese Academicians, and jointly launched by Chinese ecologists at home and abroad, with the aim to promote the development of modern ecology in China and strengthen international comunication and cooperation between ecologists. The 6th International Symposium on Modern Ecology Series (ISOMES) was hosted by Nanjing University on August 1-6, 2011 in Nanjing. Over 400 students and scholars attended this meeting. According to the meeting's theme "Global Change and Hot Issues in Modern Ecology", the summary is briefly made from eight perspectives: global change and advanced methods for ecology, terristrial ecosystem response and feedback to global change, global change and biological invasions, global change and forest ecology, global change and plant physioecology, global change and restoration of degraded ecosystem, global change and forest hydrology, global change and regional management. Upon a comprehensive perspective of different disciplines, all topics in the summary were to explore the response of ecosystem to global change and the mitigation and adaptaion stratigies for global change at multiple spatial and temporal scales. In addition, some suggestions are proposed towards future improvement of the series.