Chlorantraniliprole is a kind of systemic insecticide and also so-called low risk insecticide targeting at the ryanodine receptor. Chlorantraniliprole has been recently registered for controlling the rice insect pests such as rice stem borer,rice leaf roller and rice water weevil in China. In order to investigate its non target effects, we estimated the toxicities of chlorantraniliprole on nymphs and adults of Cyrtorhinus lividipennis (Reuter), an important predator in rice ecosystem, by using the rice-stem dipping method. The rice-stem dipping method has been normally used to estimate the killing effect of the systemic insecticide to rice planthopper. The LC₅₀ and LC₁₀ of the third instar nymphs and newly emerged adults were examined. The estimated LC₅₀ and LC₁₀ on nymphs were 83.5 mg/L and 61.3 mg/L, respectively. Meanwhile, the estimated LC₅₀ and LC₁₀ on adults were 64.3 mg/L and 39.0 mg/L, respectively. These doses were higher or similar to the field recommended dose (40 mg/L) which indicates that chlorantraniliprole is a safe insecticide for natural enemies. However, the outcome from toxicity test does not necessary suggest its safety on C. lividipennis because there still are some negative effects, e.g., reduced fecundity, adult mating ability. Consequently, we investigated some negative effects by comparing the biological performance of insecticide treated or not treated of C. lividipennis. The insecticides were applied at the third instar nymph stage with 40 mg/L dosage or control. The biological characters of C. lividipennis adults were measured to estimate negative effects. The female pre-ovipositing period, ovipositing period, longevity, and fecundity were measured. These characters were significantly decreased if treated with the field recommended dose of chlorantraniliprole. The pre-ovipositing period were prelonged from 2.3 days to 3.0 days. In contrast, the ovipositing period, female longevity, and fecundity were all significantly reduced. All these changed aspects resulted into the largely reduced population growth rate of C. lividipennis which suggested that chlorantraniliprole could result a negative effect on natural enemies. Furthermore, we also investigated the potential effects of chlorantraniliprole on C. lividipennis offspring. When the 3^rd instar nymphs treated with 40 mg/L chlorantraniliprole, F1 generation eggs and nymphs had significantly extended developmental immature stages. In addition, the daily survival rate and fecundity of F1 females treated by chlorantraniliprole were significantly decreased in compared to control. For example, the averaged egg laid by untreated female was 70.5, while it was only 47.6 by treated female. We also estimated the net reproduction rate (R₀), finite rate of increase (λ), and intrinsic rates of increase (r_m) of F₁ generation. All of these parameters of treated individuals were decreased significantly in compared to untreated individuals. Especially, the net reproduction rate (R₀) of untreated population was largely reduced from 63.3 to 21.0. The calculated population doubling time (t) was extended from 3.2 d (control) to 4.3 d (treated). These results suggested that C. lividipennis can survive from the directly killing effect of the field recommended dosage (40 mg/L) of chlorantraniliprole. However, the sublethal effect of chlorantraniliprole can result a remarked negative effects on the population growth of C. lividipennis. These results would provide some evidences to apply chlorantraniliprole to harmony the insecticide and biological control against rice pest insects.