To probe the irritability of soil quality indicators on comprehensive amelioration measures applied in coastal salt-affected land of Hangzhou bay, the soil profiles in the ameliorated zone were investigated by comparisons with controls, those in the same zone before amelioration activity as temporal controls and in the wasteland and farmland nearby as procedure controls, revealing the response of soil quality indicators to comprehensive amelioration measures through three aspects as sensitivity, process and responsivity. The results showed that soil salt content, organic matter and total nitrogen(TN) were susceptible to the comprehensive amelioration measures and had a regularly changing tendency. Soil total phosphorus(TP) and available phosphorus were also sensitive to comprehensive amelioration measures but the tendency was not steady. Soil dehydrogenase activity was somewhat responsive to comprehensive amelioration measures. But soil pH, total potassium(TK), available potassium and catalase activity had no obvious responses to comprehensive amelioration measures in the period of 2 years. It was concluded that the comprehensive amelioration measures had already affected positively the quality of soil in coastal salt-affected land only after afforestation in 2 years. Salt content, organic matter and total nitrogen of soil in coastal saline land were approved to be modified easily through ecological measures, but soil pH in the same area was hard to be ameliorated. In addition, it must be pointed out that the effect of eco-control ways on the other soil indicators still needed to further probe.