Polychlorinated biphenyls (PCBs) have been widely used in production fields for their excellent chemical characteristics. However, PCBs can be accumulated through the food chain, which directly endangers human health. In May 2004, the Global Environment Facility initiated the demonstration project of PCBs management and treatment in China, specifying Zhejiang Province as the demonstration province, and carried out checking, monitoring, cleaning, treating and managing the PCBs savepoints thoroughly in Zhejiang Province. However, the poor storage conditions and improper managements of savepoints will lead to PCBs leaking and contaminating the surroundings. For this reason, 6 sampling sites were chosen to collect water, sediment and important edible and marine environmental monitoring fish-Boleophthalmus pectinirostris samples in the surrounding areas of a PCBs savepoint located in the coast of Zhejiang Province in August 2009. Contents of the most toxic 12 kinds of the Dioxin-like PCB (DL-PCB) congeners were determined by using GC-MS method. The results showed that all samples contained DL-PCBs. The total DL-PCBs concentrations of water, sediment and B. pectinirostris samples were 88.82-971.73 ng/L (with the average of 541.71 ng/L), 1.96-57.24 ng/g (with the average of 26.10 ng/g) and 59.19-301.62 ng/g lipid (with the average of 148.54 ng/g lipid) respectively. The detection rate of the mono-ortho congener PCB118 and the non-ortho congener PCB81 in all samples reached 100%. Contents of both the PCB118 and PCB81 had significant correlations with the total DL-PCBs. For water, sediment and fish samples, the correlation coefficient (r) values between PCB118 and total DL-PCBs were 0.97, 0.95 and 0.91 respectively, and the rvalues between PCB81 and total DL-PCBs were 0.93, 0.99 and 0.98 respectively. The level of low chloride congeners (PCB81 and 77) was higher in environmental samples, while high chloride congeners (PCB118 and 105) were the main components of biological samples. The average concentration coefficient for B. pectinirostris from the waters and sediments around the PCBs savepoint were 392.54 and 14.03-fold respectively, and there was a high correlation between the DL-PCBs contents of fish and sediments (r=0.97). Waters and sediments within 150 m away from the estuary site had a high level of PCBs concentration (exceed 599.34 ng/L and 10.97 ng/g, respectively), and all the PCBs contents of B. pectinirostris exceeded 59.19 ng/g lipid, which was markedly higher than other areas. The toxic equivalency (TEQ) study indicated that the non-ortho congeners PCB126 and PCB169 were the main contribors for the total TEQs, and all the TEQs values of water and fish samples largely exceeded the Japanese water environment standard (1 pg TEQ/L) and the European Union's aquatic standard (8 pg TEQ/g) (P<0.001). By means of MacDonald's sediment toxicity assessment, the 1-4＃ sediment samples were revealed at a certain degree of toxicity risks. Considering both the PCBs content and toxic equivalency analysis, after 4 years of being dug and cleaned, this PCBs savepoint still had toxicity risks to the surrounding tidal flat ecosystem and was a potential threat to human health. The results also revealed that it was very necessary and urgent to conduct research on the environmental distributions of PCBs and assess PCBs toxicity risks to the wildlife and human health in surrounding areas of the PCBs savepoints.