The Yellow River Delta is one of the most active regions of land-ocean interaction among the large river deltas in the world. However, the wetlands in Yellow River Delta have been suffering from soil salinity and increasing degradation, because of the coastal erosion and drying up of the Yellow River. Therefore, it's essential to develop efficient eco-remediation methods on heavily degraded coastal saline-alkaline wetlands to protect wetlands resources. To study the ecological effects of Suaeda salsa on repairing heavily degraded coastal saline-alkaline wetlands, ploughing (PG), fertilization (FG) and reed debris (RD) were used for soil eco-remediation. The saline-alkaline soil eco-remediation effects were investigated by periodic measurements of such variables as soil salt content, Na⁺, soil urease, phosphatase, soil nutrient components and biomass, density and yield of Suaeda salsa plant. The dynamic changes of different index and the differences of three eco-remediation methods were discussed. The results showed that the Suaeda salsa plant could grow well after the soil eco-remediation on heavily degraded coastal saline-alkaline wetlands. All three eco-remediation methods could decrease the soil salt content efficiently. The Na⁺ content in the eco-remediated soil was significantly lower than in control soil. Among three methods, the Na⁺ content in RD was significantly lower than in other two groups. The activity of soil urease and phosphatase in eco-remediation groups were higher than control, which indicated that the soil fertility was significantly improved. Compared with three methods, the activity of soil urease and phosphatase in RD was the highest. The contents of total N in PG, FG and RD were increased 30.9%, 31.7% and 28.6% respectively, and the content of total organic C, available P and K did not rise significantly. Plant biomass is one of the most important indicator evaluating the plant growth condition. Compared with three methods, the density of Suaeda salsa plant was FG < PG < RD, and the biomass of Suaeda salsa plant was PG < FG < RD. The results together indicated that organic matter adding is an effective way for soil eco-remediation in heavily degraded coastal saline-alkaline wetlands.