The growth, zinc tolerance, enrichment features and antioxidant enzyme activity of Armillara mellea under zinc stress were investigated. Our results show that zinc at 45mg/L increased mycelia growth(P＜0.05), when higher than 90mg/L, zinc functions to inhibit mycelia growth(P＜0.05). Fruiting body formation and fruiting body biomass were not influenced by zinc when zinc content in media were less than 45mg/L(P＞0.05), but fruiting body formation was inhibited when zinc content in media were more than 90mg/L. Under the concentration of 270mg/L of supplemented zinc, the content of zinc in crustose aerial hypha of A. mellea elevated along with increasing amount of zinc in media, and under the concentration of 135mg/L of supplemented zinc, the content of zinc in rhizomorphs of A. mellea elevated along with increasing amount of zinc in media. The activity of antioxidative enzymes including peroxidase (POD), catalase (CAT) and superoxide dismutase (SOD) in crustose aerial hypha and rhizomorphs of A. mellea elevated and the activity of polyphenoloxidase (PPO) increased earlier and depressed later along with increasing amount of zinc in media, but there were observable differences between crustose aerial hypha and rhizomorphs(P＜0.05).