Both Pomacea canaliculata and Ipomoea cairica are invasive species that are very harmful to ecosystems and rice production in Southern China. It is a “one stone two birds” strategy that to use an invasive plant I. cairica for controlling another invasive animal P. canaliculata. Ethanol extract of I. cairica toxic effects on P.canaliculata and its effects on O. sativa seedling growth were evaluated in pot culture. In sand pot culture conditions, the water solutions of the ethanol extract of I. cairica and its isolated phases toxic effects on P. canaliculata were significantly different. Both the toxic effects on P.canaliculata and the promoting effects on rice seedling growth were ethanol extract, methanol phase, ethylacetate phase, and ether phase in decreasing order. In the tested concentration range, the higher concentration of the water solutions both of ethanol extract of I. cairica and its isolated phases were, the stronger both toxic effects on P. canaliculata and promoting effects on the growth of rice seedling revealed. In pot culture with paddy soil conditions, it showed no significant differences between ethanol extract of I. cairica and Mita, which is an ordinary molluscicide, to reduce P. canaliculata grazing rice seedling(p>0.05). Furthermore, the ethanol extract of I. cairica promoted the growth of rice seedling slightly than that of cultured either in water or Mita solution. The ethanol extract of I. cairica showed toxic effect on P. canaliculata indeed, but it showed no harmful effects, and even somehow promoting effects on the growth of rice seedling. Obviously, it is a potential non-chemical method to use I. cairica to mange P. canaliculata in rice production, and it has a better applying prospect which is valuable done further investigations.