In order to assess the ecological impact of chemical discharges on intertidal macrozoobenthos, the community distribution of macrozoobenthos was investigated in intertidal zone of Chemical Industrial Park and adjacent area, Jiaojiang Estuary. Field sampling of macrozoobenthos was carried out including six intertidal sections in Oct. 2007 and Jan. 2008. The results showed that: (1) A total of 75 macrozoobenthos species were obtained, of which 64 species were found in autumn and 29 species in winter; (2) The distribution of macrozoobenthos species number showed an increasing trend from inner to outer estuary; (3) The macrozoobenthos species was significantly different in soft-intertidal zone between the Chemical Industrial Park and adjacent area, despite of similar biomass and density; (4) Compared with other estuaries in China, more macrozoobenthos species were found in Jiaojiang Estuary, which may be related with its wide estuarine gate geographically.