Effects of alkalinity (ALK) and pH on the survival, growth and reproduction of two strains of Moina mongolica (Jinnan and Neimeng strain) were investigated under temperature of (25±0.5)℃ and salinity of (31.5±0.5). In pH experiment, the results showed that growth and survival rate of M. mongolica in pH 6-8 groups were significantly higher than those in other groups. The highest intrinsic increase rates (rm) of Jinan and Neimeng strain were 0.5758 and 0.5519 ind·d-1, respectively. In ALK experiment, M. mongolica reared at ALK of 2.05-4.58 mmol·L-1 showed significantly higher growth and survival rate than those at other ALK groups. The highest rm of Jinan and Neimeng strain were 0.5573 and 0.5376 ind·d-1, respectively. There was no significant difference in growth of body length between two strains of M. mongolica under the same experimental condition, while Jinan strain of M．mongolic showed higher reproduction parameters than those of Neimeng strain. The above results indicated that optimal pH and ALK for survival of two strains of M. mongolica were pH 6-8 and ALK 2.05-4.58 mmol·L-1, respectively. The adaptability to alkalinity and pH of Jinan strain of M．mongolica is better than that of Neimeng strain.