Eggplant verticillum wilt is one of soil-borne diseases caused by Verticillum dahliae With the development of protected and specialized vegetable production. How to control the occurrence of soil-borne plant diseases by using of the principle of allelopathy is now the focus.According to researches, plant resistances to soil-born diseases related closely to the microbial population in rhizosphere. The composition and population of microorganism in rhizosphere had the effects on avoiding the infection of pathogen. Fructus cnidii and Radix Sophorae Flavescentis were screened out of 54 plant extracts with their resistance to Verticillum dahliae activity. The fruit of Fructus cnidii and the root of Radix Sophorae Flavescentis were used as plant materials in this research. The results showed that extract of Fructus cnidii had inhibitory effects on mycelia growth of Verticillum dahliae in vitro, and the higher the concentration, the greater the inhibitory effects. Treatment with concentration 20 g/L showed desired inhibitory effects and the inhibitory rate hit 79.33% after 8 days treated. Extracts of Radix Sophorae Flavescentis had positive, but less efficient effects on mycelia growth of Verticillum dahliae 8 days later the inhibitory rate with concentration 20 g/L reached 68.46%. The growth parameters of potted eggplant such as plant height, stem diameter, fresh weight above ground and fresh root weight increased significantly after treated with powder of Fructus cnidii and Radix Sophorae Flavescentis. C. monniere and S.flavescens treatments, influenced the population and composition of microorganisms in the rhizosphere. The quantity of fungi in CK was higher than that in Fructus cnidii and Radix Sophorae Flavescentis, which reached 46.52×105/g at flowering and gradually decreased at fruit stage. As for the bacterium, the highest and the lowest quantity appeared in CK and Radix Sophorae Flavescentis at flowering stage. The bacterium quantity in Fructus cnidii treatment hit 41.76×108/g at flowering stage. The quantity of actinomyces increased after treatments and reached 3938×107/g at flowering stage. Less quantity of actinomyces was found in Cnidium monnieri than that in Radix Sophora Flavescens. It seems that allelopathic substances released by C.monnirei and S. flavescens were suppressive to Verticillium dahliae.