The mice had lots of aberrant behaviour in lab conditions. The behaviour of the thely-mice were observed of the jumping mice and non-jumping mice of F1 and parential generations. Regularity of the social behaviour and the relationship of the concentration of the corticosteroid and the aberrant behaviour of mice in continued generations were also studied. The results indicated that aberrant behaviour was significant difference between the jumping mice and the non-jumping mice（P<0.05）.The hours of sleeping were significantly longer for the non-jumping mice than those in the jumping mice（P<005）. The frequency of decorating behaviour for the non-jumping mice was significantly more than that in the jumping mice（P<0.05）. The frequency of searching behaviour for the jumping mice was significantly more than the non-jumping mice（P<0.05）.The types of the aberrant behaviour of the jumping mice of F1 were the similar to those of the parential generation. The concentration of corticosteroid of the jumping mice was higher than that of the non-jumping mice (P<0.05). The results suggested that the secretory of corticosteroid influenced the frequency of the aberrant behaviour of mice.