In recent years,the ecological environment of west China has encountered serious problems. On one hand, large piles of manure from livestock have caused environmental pollution,while a large amount of vegetation has been destroyed to meet the rural energy shortage,which leads to further ecological degradation. Biogas projects have been rapidly developed because they can deal with the animal wastes while providing energy. However,the rapid development of biogas projects has also introduced a further difficulty of biogas slurry treatment and utilization,which has became the primary limiting factor for further development of biogas projects and the sustainable development of agriculture in west China. Therefore,it is necessary to conduct research on the technologies for biogas slurry treatment and utilization. The effects of application of biogas slurry from swine farms on seven different vegetable pathogens,namely Fulvia fulva,Botrytis cinerea pers,Aletnaria solani,Phytophthora capsici Len,Pythium aphanidermatum, Glomerella cingulata var orbicularis Jenkins Winstead et mc Combs,Botrytis cinerea, were studied in vitro using the plate diffusion method. The results showed that the inhibition of biogas slurry was different for different pathogens. The fresh biogas slurry strongly inhibited the growth of Botrytis cinerea pers, Aletnaria solani, Phytophthora capsici Len, Glomerella cingulata var orbicularis Jenkins Winstead et mc Combs and Botrytis cinerea. The fresh filtrate of biogas slurry had obvious inhibitory effects on Botrytis cinerea pers and Botrytis cinerea. The inhibitory rates were affected by the time the biogas slurry was applied, and the inhibitory rates on Botrytis cinerea pers, Aletnaria solani, Botrytis cinerea did not change significantly with the time of the application. The biogas slurry application at certain time had higher inhibitory rates on Phytophthora capsici Len and Glomerella cingulata var orbicularis Jenkins Winstead et mc Combs. No significant difference was observed between the inhibitory effect of filtrate of biogas slurry applied at different time on Botrytis cinerea pers and Botrytis cinerea. Test results showed that biogas slurry from swine farms can play a role in the prevention and treatment of certain vegetables diseases. The application of biogas slurry for vegetable disease control provides an argument for the sustainable development of biogas while reducing the use of pesticides and restoring the ecological environment. It has great practical benefit and likelihood of adoption,especially in the ecologically- fragile areas of western China.