Giant panda is the flagship species for priority ecological protection. The demonstration effect as well as scientific values in protecting giant pandas and their habitats are of great significance. China is committed to building natural reserve system with national parks as the main body, aiming at restoring the integrity and connectivity of giant panda habitats. Therefore, analyzing the ecological security of the giant panda reserves and providing theoretical basis for the establishment of the giant panda National Park are very important.Taking Sichuan Province as an example, this paper, based on data from 20 typical counties that would be included as the conservation areas of giant pandas in the future, is to establish an ecological security evaluation index system for giant panda protected areas. The comprehensive evaluation was carried out by using entropy weight and analytic hierarchy process method,and temporal and spatial dynamic analysis of the ecological security of the giant panda protection site, as well as spatial correlation analysis. The results showed that: (1) From 2003 to 2017, the comprehensive index of ecological security of giant panda conservation areas in Sichuan Province showed a volatility upward trend and the ecological environment improved significantly,whereas environmental degradation in some counties still exists. (2) The ecological security status of each county showed strong differences, and there was significant spatial positive correlation and spatial clustering in the ecological security index of adjacent counties; (3) The contradiction between the ecological security of the giant panda conservation area and the surrounding social and economic development levels is still serious, and the interaction between economic development and ecological protection status of the adjacent counties is obvious. Therefore,the paper suggests to promote ecological balance with the solution of joint managment to protect and improve giant pandas and their habitats.