CO₂, CH₄, and N₂O, have strong warming potentials and are considered to be the primary greenhouse gases in the atmosphere. Global warming caused by the increasing concentrations of atmospheric CO₂, CH₄, and N₂O is one of the hotspots in global change field. Greenhouse gas (GHG) fluxes in reed wetlands are critical in evaluating the source/sink strength of GHG in arid area. We studied the dynamics of soil CO₂, CH₄, and N₂O fluxes using static chamber-based on gas chromatography in two reed wetlands of the freshwater Bosten Lake, located in an arid area of Northwestern China. During a full year of monitoring, environmental variables (including soil moisture, soil temperature, air temperature, pH and salinity) were measured to determine the effects of abiotic factors on soil CO₂, CH₄, and N₂O fluxes in artificial and natural reed wetlands. SPSS 19.0 for Windows was used to analyze the relationships between environmental factors and soil CO₂, CH₄, and N₂O fluxes. The results showed that soil CO₂, CH₄, and N₂O fluxes in the artificial reed wetland were 10.1-588.4mg m^-2 h^-1, 1.32-29.7μg m^-2 h^-1 and 3.1-64.8μg m^-2 h^-1, respectively, which was comparable with the values from the natural reed wetland. Higher soil CO₂ emissions occurred in summer, whereas CH₄ and N₂O emissions mainly occurred in late spring and early summer. Temperature was the main factor controlling soil CO₂ and N₂O fluxes in both reed wetlands (P < 0.01). Soil CH₄ emission flux was affected by both temperature and moisture. According to regression analysis, the combination of near-surface temperature, top 5cm soil temperature, and soil water content could explain 71% and 74.5% of soil CH₄ flux in artificial and natural reed wetlands, respectively. Soil organic carbon, pH, salinity, NH₄⁺-N, and NO₃^--N are also influencing factors of CO₂, CH₄, and N₂O fluxes in artificial and natural reed wetlands. However, the differences in CO₂, CH₄, and N₂O emissions from soils of artificial and natural reed wetlands were caused by differences in soil organic carbon, soluble nitrogen, and biomass. Based on the centennial scale, the soils of artificial and natural reed wetland were "sources" of GHG, and the global warming potential from artificial reed wetland was higher than that from natural reed wetland.