With the development of China, government is coming to realize the important of the nature and ecology conservation. In recent ten years, the government has set up many national key regions of ecological protection, and taken lots of effective measures to protect nature and ecology, then supporting the sustainable development. These regions mainly include National Key Ecological Function Region (KEFR), National Important Ecological Function Region (IEFR), National Biodiversity Protection Priority Region (BPRR) and National Natural Reserve Region (NNPR). It is well known to us that vegetation is one of the most important and active ecological element, and vegetation growth in national important ecological protection region is very important for maintaining stabile structure and function of regional ecosystem. In this paper, these national key regions are taken as the study region, cumulative NDVI is taken as the instruction factor, and vegetation growth is monitored and evaluated. Based on the SPOT VEGATATION NDVI from 1998 to 2007, mean value, standard deviation and linear change trend coefficient this period are calculated, and spatio-temporal statistical feature of vegetation growth is analyzed. The results show that: (1) Total area of the important ecological protection regions is 536.59 km², accounting for 55.89% of the national land area. BPRR and KEFR and IEFR overlapped area is up to 53.36% and 50.20% of the total corresponding ecological function area respectively. NNPR and the other three types of area overlapped area are good, especially with KEFR, its area accounts for 75.10% of NNPR. For KEFR and IEFR, overlapped area is respectively 63.73% and 39.15% of the corresponding types regions. (2) About general vegetation growth from 1998 to 2007 in these regions, middle and eastern area is better than that of the western regions. About the vegetation growth, there is about 10.59% in poor level, about 29.59% in common level, about 23.44% in well level, and about 36.39% in better level. NNPR and BPRR are better than KEFR and IEFR. The difference of spatial distribution is the most remarkable. (3) About change trend of vegetation from 1998 to 2007 in these regions, general trend in these regions is a slightly increasing. 62.39% of these regions is a relatively stable trend, 22.69% of these regions is in a better trend, 14.93% of these regions is in a bad trend. IEFR is the most obvious vegetation trend, the second is BPRR. BPRR in the different of change trend is maximum, NNPR is minimum. For different types of national ecological protection areas, these results are different beneficial to different national important ecological protection region. For NNPR, these can reflects the effectiveness of the protection after their establishment in a certain extent. For others, these can be used as the background of the ecological state, and carried out the analysis of the effectiveness of national ecologically important protected areas in the future.